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KMID : 0356919770100020101
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Korean Journal of Anesthesiology
1977 Volume.10 No. 2 p.101 ~ p.105
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Serum Testosterone in Man during Methosyflurane Anesthesia and Surgery
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Abstract
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The relationship between the Leydig cell of testis and the tropic hormones of the anterior pituitary gland has been inadequately explored in man because of methodological difficulties.
A report has appeared on the effect of anesthesia per se on sex gormone levels in human serum. As testosterone is one of the most important anabolic hormonces, it would therefore serve as an index to hormonal response to stress in man.
Testicular blood level of testcsterone is man was increased by ether anesthesia but plasma testosterone in man was decreased by halothane anesthesia.
Plasma testosterone levels were measured by others. by a competitive protein binding method.
This study was performed to investigate the effect of methoxyflurane anesthesia and surgery on human sex hormone by a radioimmunoassay method.
Serum testosterone levels measured in the pre-anesthetic period, 60 minutes after anesthesia and surgery, and at full recovery from anesthesia were 3.80±1.75 ng/ml, 3.58±1.22 ng/ml and 3.55±1.85 ng/ml, respectively.
No statistical significance was observed.
The obtained value of testosterone was the lowest when compared with the values reported by others.
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